Pfam Domains GO Terms
| Arb2 |
| chromatin silencing by small RNA |
| siRNA binding |
| chromatin organization involved in negative regulation of transcription |
| chromatin silencing |
| regulation of alternative mRNA splicing, via spliceosome |
| chromatin organization involved in regulation of transcription |
| neural crest cell development |
| negative regulation of gene expression, epigenetic |
| stem cell development |
| mesenchymal cell development |
| gene silencing by RNA |
| neural crest cell differentiation |
| regulation of mRNA splicing, via spliceosome |
| regulation of RNA splicing |
| regulation of mRNA processing |
| gene silencing |
| mesenchymal cell differentiation |
| stem cell differentiation |
| mesenchyme development |
| regulation of gene expression, epigenetic |
| regulation of mRNA metabolic process |
| RNA splicing |
| mRNA processing |
| mRNA metabolic process |
| chromatin organization |
| RNA processing |
| endoplasmic reticulum |
| chromosome organization |
| negative regulation of transcription, DNA-templated |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| negative regulation of RNA metabolic process |
| negative regulation of cellular macromolecule biosynthetic process |
| negative regulation of nucleobase-containing compound metabolic process |
| negative regulation of macromolecule biosynthetic process |
| negative regulation of cellular biosynthetic process |
| negative regulation of biosynthetic process |
| cell development |
| RNA metabolic process |
| negative regulation of gene expression |
| tissue development |
| gene expression |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution