Table of Contents
Dimethyl-Sulfoxide 1pc R03 exp120
Mechanism of Action
Technical Notes
Screen Summary
Screen Results
Dimethyl-Sulfoxide 1pc R03 exp120
Mechanism of Action
N/A
Class / Subclass 1:
Chemogenomic Negative Control / Solvent
Technical Notes
Protein References
PubChem Name:
Dimethyl sulfoxide
Synonyms:
N/A
CAS #:
67-68-5
PubChem CID:
679
IUPAC:
methylsulfinylmethane
INCHI Name:
InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
INCHI Key:
IAZDPXIOMUYVGZ-UHFFFAOYSA-N
Molecular Weight:
78.14
Canonical SMILES:
CS(=O)C
Isomeric SMILES:
N/A
Molecular Formula:
C2H6OS
Protein Supplier
Supplier Name:
Corning
Catalog #:
25-950-CQC
Lot #:
N/A
Protein Characterization
HRMS (ESI-TOF) m/z:
(M+Na)+ Calcd for C2H6OS 101.00316; found 101.00155
Dose Response Curve
Dose response curve not available.
Screen Summary
Round
: 03
Dose
: 1%
Days of incubation
: 8
Doublings
: 4.1
Numbers of reads
: 10652331
Screen Results
Sensitive/Resistant hits (FDR<0.05)
CRANKS
Score Plot
Top 30 Genes
Screen Similarity
Top 30 Sensitive GO terms
Top 30 Resistant GO terms
0/7
Scores
View
View
View
View
View
×
Dimethyl-Sulfoxide 1pc R03 exp120
×
Top 30 S/R Genes
Gene
CRANKS Score
FDR
SPI1
-2.89
0.08
CHPF2
-2.71
0.18
XPOT
-2.65
0.08
TCF4
-2.62
0.23
C2orf78
-2.46
0.15
IRF4
-2.41
0.24
FPGS
-2.29
0.56
CALCR
-2.25
0.24
UBE3A
-2.17
0.33
SORL1
-2.14
0.35
UBE2L3
-2.10
0.38
BCL2
-2.09
0.38
DHDDS
-2.08
0.74
OR4P4
-2.05
0.55
DNAJC3
-2.03
0.49
GATSL3
-2.03
0.55
DNAJC27
-2.02
0.55
TOR1B
-2.01
0.55
GNA13
-1.99
0.55
TRIP10
-1.99
0.56
EEFSEC
-1.96
0.63
CHKA
-1.94
0.55
SBSN
-1.93
0.67
FAIM2
-1.93
0.55
COPE
-1.93
0.78
HOXA6
-1.92
0.55
GTF2H5
-1.91
0.55
PRKAR1A
-1.90
0.55
KPTN
-1.90
0.73
GALNT6
-1.88
0.73
RFX7
2.05
0.27
DVL3
2.07
0.28
PLXDC1
2.07
0.28
TM2D3
2.08
0.25
ELF1
2.09
0.25
LGALS3BP
2.09
0.25
SIRT6
2.09
0.34
MTBP
2.10
0.25
ACSL4
2.10
0.25
ZNF773
2.11
0.28
MEP1A
2.13
0.25
FAM50A
2.17
0.57
TTC36
2.18
0.27
CCDC79
2.21
0.28
CAMKK2
2.21
0.21
EIF3E
2.22
0.35
HMGN2
2.23
0.28
FAM58A
2.25
0.19
POLD3
2.35
0.60
KLF16
2.43
0.25
UPF2
2.44
0.34
MAPKAP1
2.59
0.07
CDK12
2.66
0.23
TNPO1
2.70
0.04
TOX4
2.73
0.04
PRR14L
2.74
0.04
CEP57
2.80
0.04
SPOP
3.12
<0.01
MEMO1
3.34
<0.01
SART3
3.52
0.04
×
Correlated Screens
Screen
Correlation
Plot
I-BRD9 4μM R07 exp365
0.061
View
×
Dimethyl-Sulfoxide 1pc R03 exp120 vs I-BRD9 4μM R07 exp365
×
Top 30 sensitive GO terms
No GO term hits below threshold. (FDR <0.05)
×
Top 30 resistant GO terms
No GO term hits below threshold. (FDR <0.05)