PRR14L [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: PRR14L
Official Name: proline rich 14 like
Aliases and Previous Symbols: N/A
Entrez ID: 253143
UniProt: Q5THK1
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
BI-2536 0.0042μM R03 exp95	-3.17
BI-6727 0.0125μM R03 exp97	-3.12
GSK461364A 0.005μM R03 exp125	-3.08
BI-2536 0.02μM R03 exp96	-2.39
MLN-4924 0.2μM R00 exp21	-2.18
SGC0649 7μM R03 exp150	-1.98
Demecolcine 0.03μM R05 exp228	-1.9
THZ531 0.11 to 0.125μM on day4 R07 exp410	-1.89
DABN 20μM R00 exp17	-1.81
Taxol 0.004μM R03 exp103	-1.78
LY2090314 0.003μM R08 exp499	1.74
TNF-alpha 44ng/ml R08 exp533	1.79
Arsenic trioxide 60μM R08 exp449	1.83
Tunicamycin 0.04 to 0.125μM on day4 R07 exp420	1.83
ETC-159 50μM R08 exp480	1.84
Rapamycin 2μM R07 exp306	1.85
Ethanol 0.01 R05 exp234	1.96
Hydroxyurea 15μM R06 exp289	1.97
Tunicamycin 0.04 to 0.075μM on day4 R07 exp419	2.05
YM155 0.001μM R08 exp432	2.37
Tunicamycin 0.04μM R07 exp418	2.49
Vemurafenib 6.6μM R08 exp434	2.59
Dimethyl-Sulfoxide 1pc R03 exp120	2.74
I-BRD9 4μM R07 exp365	3.14

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 15339
Expression level (log2 read counts): 6.89

Expression Distribution

Last modified: 2025/12/10 20:19
by 127.0.0.1