C2CD3

• Official Symbol: C2CD3
• Official Name: C2 domain containing 3 centriole elongation regulator
• Aliases and Previous Symbols: N/A
• Entrez ID: 26005
• UniProt: Q4AC94
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a protein that functions as a regulator of centriole elongation. Studies of the orthologous mouse protein show that it promotes centriolar distal appendage assembly and is also required for the recruitment of other ciliogenic proteins, including intraflagellar transport proteins. Mutations in this gene cause orofaciodigital syndrome XIV (OFD14), a ciliopathy resulting in malformations of the oral cavity, face and digits. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014].
• UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 7520
• Expression level (log2 read counts): 6.32

Expression Distribution

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C2CD3 Expression in NALM6 Cells: 6.32