NOL7 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: NOL7
Official Name: nucleolar protein 7
Aliases and Previous Symbols: N/A
Entrez ID: 51406
UniProt: Q9UMY1
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Oligomycin-A 20μM R00 exp26	-1.92
SNS-032 15μM R08 exp443	-1.82
Etoposide 10μM R00 exp20	-1.76
Wiskostatin 3μM R07 exp422	1.7
Hydroxyurea 15μM R06 exp289	1.75
2-Methoxyestradiol 0.55μM R07 exp310	1.77
Nifuroxazide 5μM R03 exp102	1.95
THZ531 0.225μM R08 exp444	2.15

Gene	Correlation
RRM1	0.461
EBNA1BP2	0.439
NCL	0.426
KCTD17	0.419
RPS2	0.415
AKAP1	0.412
UTP3	0.411
SLC6A17	0.41
TBC1D3H	0.408
ACSF2	0.405
PWP2	0.4

Global Fraction of Cell Lines Where Essential: 98/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	3/28
blood	2/28
bone	3/26
breast	2/33
central nervous system	7/56
cervix	1/4
colorectal	2/17
esophagus	2/13
fibroblast	0/1
gastric	2/16
kidney	3/21
liver	2/20
lung	10/75
lymphocyte	2/16
ovary	4/26
pancreas	5/24
peripheral nervous system	2/16
plasma cell	2/15
prostate	1/1
skin	4/24
soft tissue	1/9
thyroid	0/2
upper aerodigestive	3/22
urinary tract	7/29
uterus	1/5

Essentiality in NALM6

Essentiality Rank: 1761
Expression level (log2 read counts): 6.11

Expression Distribution

Last modified: 2025/12/10 20:19
by 127.0.0.1