SLC1A5
Gene Information
- Official Symbol: SLC1A5
- Official Name: solute carrier family 1 member 5
- Aliases and Previous Symbols: N/A
- Entrez ID: 6510
- UniProt: Q15758
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| SDF |
GO Terms
| L-glutamine import across plasma membrane |
| glutamine secretion |
| glutamine transport |
| L-serine transport |
| L-glutamine transmembrane transporter activity |
| L-serine transmembrane transporter activity |
| serine transport |
| neutral amino acid transmembrane transporter activity |
| amino acid import across plasma membrane |
| amino acid import |
| protein homotrimerization |
| amino acid transmembrane transporter activity |
| neutral amino acid transport |
| symporter activity |
| L-alpha-amino acid transmembrane transport |
| protein trimerization |
| L-amino acid transport |
| drug transmembrane transport |
| virus receptor activity |
| amino acid transmembrane transport |
| acid secretion |
| viral entry into host cell |
| import across plasma membrane |
| melanosome |
| entry into host |
| entry into host cell |
| amino acid transport |
| organic acid transmembrane transport |
| carboxylic acid transmembrane transport |
| drug transport |
| interaction with host |
| viral life cycle |
| signaling receptor activity |
| anion transmembrane transport |
| organic acid transport |
| carboxylic acid transport |
| protein homooligomerization |
| organic anion transport |
| protein complex oligomerization |
| anion transport |
| cation transmembrane transport |
| import into cell |
| viral process |
| symbiotic process |
| interspecies interaction between organisms |
| cation transport |
| ion transmembrane transport |
| secretion by cell |
| response to drug |
| export from cell |
| secretion |
| transmembrane transport |
| ion transport |
| integral component of plasma membrane |
| protein-containing complex assembly |
| nitrogen compound transport |
| protein-containing complex subunit organization |
| membrane |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| RRM1 | 0.447 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 8/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 1/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 1/17 |
| esophagus | 1/13 |
| fibroblast | 0/1 |
| gastric | 1/16 |
| kidney | 1/21 |
| liver | 1/20 |
| lung | 0/75 |
| lymphocyte | 1/16 |
| ovary | 0/26 |
| pancreas | 1/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 10362
- Expression level (log2 read counts): 8.58
Expression Distribution
SLC1A5 Expression in NALM6 Cells: 8.58