TRIT1

Gene Information
  • Official Symbol: TRIT1
  • Official Name: tRNA isopentenyltransferase 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 54802
  • UniProt: Q9H3H1
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1337
  • Expression level (log2 read counts): 4.77

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1