ABCA5
Gene Information
- Official Symbol: ABCA5
- Official Name: ATP binding cassette subfamily A member 5
- Aliases and Previous Symbols: N/A
- Entrez ID: 23461
- UniProt: Q8WWZ7
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008].
- UniProt Summary: May play a role in the processing of autolysosomes. {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 17663
- Expression level (log2 read counts): 4.59
ABCA5 Expression in NALM6 Cells: 4.59
