ATAD1
Gene Information
- Official Symbol: ATAD1
- Official Name: ATPase family AAA domain containing 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 84896
- UniProt: Q8NBU5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA- stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent (By similarity). {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 10152
- Expression level (log2 read counts): 6.49