DDX6

Gene Information
  • Official Symbol: DDX6
  • Official Name: DEAD-box helicase 6
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 1656
  • UniProt: P26196
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: In the process of mRNA degradation, plays a role in mRNA decapping (PubMed:16364915). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts (PubMed:26098573). {ECO:0000269|PubMed:16364915, ECO:0000269|PubMed:26098573}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1505
  • Expression level (log2 read counts): 8.17

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1