MTMR9

Entrez Summary: N/A
UniProt Summary: Probable pseudophosphatase. Contains a Gly residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential). {ECO:0000305}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

regulation of phosphatidylinositol dephosphorylation
enzyme regulator activity
positive regulation of phosphatase activity
positive regulation of dephosphorylation
negative regulation of autophagy
regulation of phospholipid metabolic process
protein phosphatase binding
ruffle membrane
phosphatidylinositol biosynthetic process
phosphatidylinositol metabolic process
regulation of phosphatase activity
protein stabilization
glycerophospholipid biosynthetic process
regulation of dephosphorylation
glycerolipid biosynthetic process
phospholipid biosynthetic process
negative regulation of cellular catabolic process
regulation of protein stability
glycerophospholipid metabolic process
negative regulation of catabolic process
regulation of autophagy
phospholipid metabolic process
glycerolipid metabolic process
regulation of lipid metabolic process
organophosphate biosynthetic process
endocytosis
lipid biosynthetic process
protein-containing complex
import into cell
perinuclear region of cytoplasm
positive regulation of hydrolase activity
regulation of cellular catabolic process
organophosphate metabolic process
cellular lipid metabolic process
regulation of catabolic process
endoplasmic reticulum
positive regulation of phosphorus metabolic process
positive regulation of phosphate metabolic process
lipid metabolic process
regulation of hydrolase activity