SLC25A52 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: SLC25A52
Official Name: solute carrier family 25 member 52
Aliases and Previous Symbols: N/A
Entrez ID: 147407
UniProt: Q3SY17
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Phenformin 20μM R03 exp143	1.81
Arsenate 40μM R06 exp264	1.91
iCRT14 30μM R08 exp492	1.95
Nutlin-3A 1.6μM R06 exp294	1.96
Phenformin 20μM R05 exp212	1.98
Genistein 15μM R07 exp360	2.11
Mubritinib 0.2μM R02 exp65	2.26
Rotenone 0.07μM R08 exp431	2.26
AICAR 240μM R03 exp116	2.33
Chloramphenicol 20μM R00 exp13	2.4
HMS-I2 10μM R06 exp288	2.56
Oligomycin-A 2μM R00 exp25	2.78
QNZ 0.01μM R08 exp439	2.89
AICAR 240μM R05 exp211	2.98
Mubritinib 0.2μM R01 exp48	3.94

Gene	Correlation
NDUFA1	0.458
NDUFB11	0.457
NDUFB9	0.448
NDUFAF7	0.441
NDUFA2	0.437
ATP5O	0.431
HSD17B10	0.43
DARS2	0.429
NUBPL	0.429
ATP5A1	0.429
BCS1L	0.428
NDUFC2	0.427
GATC	0.423
PARS2	0.422
ATP5C1	0.422
MTHFD1L	0.421
MTRF1L	0.42
MRPL21	0.419
ACAD9	0.419
LARS2	0.419
RARS2	0.416
NARS2	0.416
WBSCR16	0.415
RTN4IP1	0.415
NDUFS2	0.415
DAP3	0.412
QRSL1	0.411
MRPL45	0.409
ATP5D	0.409
NDUFAF5	0.408
TIMMDC1	0.406
MRPS21	0.405
POLRMT	0.405
PGM3	0.404
NDUFB7	0.404
ATP5B	0.403
NDUFB5	0.403

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 3196
Expression level (log2 read counts): 0.11

Expression Distribution

Last modified: 2026/01/07 22:37
by 127.0.0.1