RBMX2
Gene Information
- Official Symbol: RBMX2
- Official Name: RNA binding motif protein X-linked 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 51634
- UniProt: Q9Y388
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| RRM 1 |
GO Terms
| first spliceosomal transesterification activity |
| U2 snRNP |
| U2-type precatalytic spliceosome |
| RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| mRNA splicing, via spliceosome |
| RNA splicing, via transesterification reactions |
| RNA splicing |
| mRNA processing |
| mRNA metabolic process |
| RNA processing |
| RNA binding |
| RNA metabolic process |
| gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| HARS | 0.526 |
| RPE | 0.487 |
| GTF3C3 | 0.471 |
| LSM10 | 0.459 |
| GTF3C2 | 0.457 |
| UHRF1 | 0.456 |
| AASDHPPT | 0.454 |
| TRIAP1 | 0.454 |
| GTF3C6 | 0.452 |
| PIK3R4 | 0.448 |
| HCCS | 0.445 |
| CCT7 | 0.445 |
| VRK1 | 0.444 |
| CHCHD4 | 0.444 |
| TELO2 | 0.44 |
| TRIP12 | 0.434 |
| EIF3F | 0.434 |
| VEZT | 0.43 |
| BCS1L | 0.429 |
| THG1L | 0.427 |
| MRPS11 | 0.425 |
| SRP14 | 0.423 |
| ENO1 | 0.418 |
| RPTOR | 0.416 |
| ADSL | 0.416 |
| ALG1 | 0.415 |
| HAUS8 | 0.41 |
| DOHH | 0.41 |
| ATXN10 | 0.409 |
| GMPPB | 0.408 |
| APAF1 | 0.408 |
| LAMTOR3 | 0.404 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 138/694
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 1/1 |
| 909776.0 | 1/1 |
| bile duct | 8/28 |
| blood | 2/26 |
| bone | 2/26 |
| breast | 10/30 |
| central nervous system | 7/49 |
| cervix | 2/4 |
| colorectal | 5/17 |
| esophagus | 1/11 |
| fibroblast | 0/1 |
| gastric | 2/14 |
| kidney | 6/18 |
| liver | 1/19 |
| lung | 11/72 |
| lymphocyte | 2/16 |
| ovary | 5/25 |
| pancreas | 2/22 |
| peripheral nervous system | 5/15 |
| plasma cell | 5/12 |
| prostate | 0/1 |
| skin | 5/20 |
| soft tissue | 2/9 |
| thyroid | 0/2 |
| upper aerodigestive | 2/22 |
| urinary tract | 1/28 |
| uterus | 1/5 |
Essentiality in NALM6
- Essentiality Rank: 10771
- Expression level (log2 read counts): 4.7
Expression Distribution
RBMX2 Expression in NALM6 Cells: 4.7
