CSDE1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
GSK591 2.6μM R03 exp128	-2.59
Benzoate 10000μM R08 exp455	-2.31
BI-2536 0.02μM R03 exp96	-2.27
HMS-I2 5μM R06 exp287	-2.23
LJH685 50μM R08 exp433	-2.06
Trimetrexate 0.03μM R08 exp535	-2.02
B02 10μM R08 exp453	-1.85
Centrinone 0.5μM R07 exp343	-1.77
CCT251545 20μM R07 exp326	-1.76
CR131-b 0.005μM R08 exp474	-1.76
Thapsigargin 0.005μM R07 exp407	-1.73
Dorsomorphin 5μM R07 exp357	-1.71
Radicicol 0.16μM R05 exp242	1.8
Colchicine 0.009μM R05 exp215	1.86
Hydroxyurea 100μM R07 exp329	1.89
Dexamethasone 0.006 to 0.015μM on day4 R07 exp352	1.95
Pyridostatin 4μM R05 exp240	1.95
CoCl2 18μM R07 exp346	2.09
UM0125461 0.74μM R02 exp84	2.13
TRAIL 5ng/ml R00 exp35	2.47
MLN-4924 0.2μM R00 exp21	2.54
TRAIL 50ng/ml R00 exp36	2.77

Gene	Correlation
STRAP	0.491

Global Fraction of Cell Lines Where Essential: 10/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	1/28
blood	0/28
bone	1/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	2/75
lymphocyte	0/16
ovary	0/26
pancreas	1/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	1/29
uterus	0/5

Expression Distribution