UBAP1
Gene Information
- Official Symbol: UBAP1
- Official Name: ubiquitin associated protein 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 51271
- UniProt: Q9NZ09
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| ESCRT I complex |
| ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway |
| intracellular transport of virus |
| host cell |
| transport of virus |
| multi-organism transport |
| multi-organism localization |
| ubiquitin binding |
| viral life cycle |
| endosome membrane |
| endosomal transport |
| ubiquitin-dependent protein catabolic process |
| modification-dependent protein catabolic process |
| modification-dependent macromolecule catabolic process |
| proteolysis involved in cellular protein catabolic process |
| cellular protein catabolic process |
| protein catabolic process |
| viral process |
| symbiotic process |
| interspecies interaction between organisms |
| cellular macromolecule catabolic process |
| Golgi apparatus |
| macromolecule catabolic process |
| organonitrogen compound catabolic process |
| proteolysis |
| protein transport |
| intracellular transport |
| peptide transport |
| amide transport |
| establishment of protein localization |
| organic substance catabolic process |
| cellular catabolic process |
| establishment of localization in cell |
| nitrogen compound transport |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| TFIP11 | 0.517 |
| PSMD11 | 0.502 |
| SYT9 | 0.483 |
| SUPT6H | 0.48 |
| RBM39 | 0.48 |
| AKIRIN2 | 0.474 |
| C1QTNF9B | 0.47 |
| ATXN1 | 0.464 |
| MYH2 | 0.462 |
| MT1E | 0.461 |
| KCTD17 | 0.459 |
| COPG1 | 0.454 |
| TERF2 | 0.451 |
| VASN | 0.451 |
| ORC6 | 0.444 |
| CHD4 | 0.441 |
| CBWD3 | 0.434 |
| PSMD3 | 0.433 |
| DNTTIP2 | 0.431 |
| TICRR | 0.43 |
| AQR | 0.43 |
| GID4 | 0.43 |
| ACSF2 | 0.429 |
| OR10G3 | 0.428 |
| RANBP2 | 0.427 |
| ORC1 | 0.426 |
| GAR1 | 0.424 |
| SCAF1 | 0.424 |
| C14orf93 | 0.422 |
| TSPY8 | 0.422 |
| THOC1 | 0.421 |
| CDCA3 | 0.42 |
| SF3A3 | 0.42 |
| MED12 | 0.42 |
| MYO1H | 0.419 |
| CDC6 | 0.417 |
| ZNF106 | 0.417 |
| SUPT5H | 0.416 |
| PSMC1 | 0.416 |
| ARCN1 | 0.416 |
| ZNF830 | 0.414 |
| TBC1D3G | 0.414 |
| VPS54 | 0.414 |
| PLK4 | 0.412 |
| CBWD5 | 0.411 |
| CIAPIN1 | 0.41 |
| ARHGEF35 | 0.409 |
| ANKLE1 | 0.407 |
| SLC4A1 | 0.407 |
| EXOSC5 | 0.406 |
| CDC73 | 0.406 |
| SMG7 | 0.405 |
| CBWD6 | 0.405 |
| USP36 | 0.405 |
| COPZ1 | 0.404 |
| HIST1H2BE | 0.404 |
| CHMP2A | 0.402 |
| SH3BP1 | 0.402 |
| COPA | 0.402 |
| NAPA | 0.402 |
| LOC643669 | 0.402 |
| PSMD7 | 0.4 |
| HAP1 | 0.4 |
| RPS12 | 0.4 |
| DTL | 0.4 |
| ANKLE2 | 0.4 |
| HGC6.3 | 0.4 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 191/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 1/1 |
| 909776.0 | 0/1 |
| bile duct | 9/28 |
| blood | 13/28 |
| bone | 5/26 |
| breast | 11/33 |
| central nervous system | 6/56 |
| cervix | 1/4 |
| colorectal | 1/17 |
| esophagus | 2/13 |
| fibroblast | 0/1 |
| gastric | 7/16 |
| kidney | 5/21 |
| liver | 3/20 |
| lung | 25/75 |
| lymphocyte | 9/16 |
| ovary | 8/26 |
| pancreas | 5/24 |
| peripheral nervous system | 1/16 |
| plasma cell | 6/15 |
| prostate | 1/1 |
| skin | 2/24 |
| soft tissue | 2/9 |
| thyroid | 1/2 |
| upper aerodigestive | 5/22 |
| urinary tract | 10/29 |
| uterus | 2/5 |
Essentiality in NALM6
- Essentiality Rank: 1597
- Expression level (log2 read counts): 5.27
Expression Distribution
UBAP1 Expression in NALM6 Cells: 5.27
