ARHGEF35

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
ONC212 0.15μM R08 exp513	-2.2
Actinomycin-D 0.001μM R00 exp3	-1.74
Olaparib 4μM R08 exp512	1.74
Cabazitaxel 0.001μM R05 exp223	1.98
Pimelic-diphenylamide-106 0.5μM R00 exp27	1.98
Alpha-Amanitin 0.5μM R00 exp5	2.09
PFI-2 4μM R05 exp239	2.2
Vinblastine 0.002μM R01 exp60	2.32
BAY-598 4μM R05 exp220	2.44
Etoposide 0.1μM R05 exp198	2.45

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution