IGFN1

Gene Information

Official Symbol: IGFN1
Official Name: immunoglobulin like and fibronectin type III domain containing 1
Aliases and Previous Symbols: N/A
Entrez ID: 91156
UniProt: Q86VF2
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
GSK-J4 1.5μM R08 exp441	-1.92
Mitomycin-C 0.06μM R08 exp503	-1.84
Doxycycline 10μM R00 exp18	1.73
Nocodazole 0.02μM R00 exp23	1.91
Cyclosporin-A 3μM R07 exp348	1.94
NFN1 0.1μM R01 exp49	2.37

Gene	Correlation
PSMD3	0.615
TCEB3CL2	0.552
TCEB3CL	0.542
TCEB3C	0.534
RPL35	0.528
POLR2J3	0.524
TBC1D3H	0.516
HIST2H3C	0.513
HIST2H3A	0.513
TBC1D3G	0.513
PSMD1	0.511
MYLK3	0.51
TBC1D3F	0.507
NARFL	0.503
ORC1	0.502
MT1E	0.501
PAN3	0.497
PSMB4	0.493
TBC1D3C	0.491
GOLGA6L1	0.489
C1QTNF9B	0.487
KCTD17	0.486
BYSL	0.482
COPE	0.479
CHD4	0.478
RPS2	0.475
NUPL1	0.474
SSH2	0.473
SF3A1	0.473
RRM1	0.472
IK	0.471
RPL6	0.469
CHAF1A	0.469
SUPT5H	0.467
PSMA6	0.466
RPS19BP1	0.463
DOCK6	0.463
VASN	0.463
NUP93	0.463
KIF3C	0.462
POLE	0.461
TWISTNB	0.459
PSMB2	0.458
AQR	0.454
CBWD5	0.452
SLC4A1	0.452
TRAIP	0.452
DDTL	0.452
SMG7	0.452
PSMA7	0.45
TBC1D3	0.45
UPF1	0.45
EXOSC5	0.449
ZNF541	0.449
CBWD3	0.448
EXOSC4	0.447
S1PR4	0.446
MYB	0.446
SNRPA1	0.444
ARHGEF35	0.444
TP53TG3B	0.444
TBC1D3L	0.443
TP53TG3	0.443
SEMA6B	0.443
TBC1D3I	0.443
TBC1D3K	0.443
RAD51	0.443
TBC1D3E	0.443
TP53TG3C	0.442
SLC6A17	0.442
SAP30BP	0.441
PCF11	0.44
RPS12	0.44
ORC6	0.439
FAM160A1	0.439
POLA2	0.438
PSMC1	0.438
SUPT6H	0.438
NUP54	0.438
FCN2	0.437
NOL10	0.435
CCNA2	0.435
ANKLE1	0.434
CDT1	0.434
CTR9	0.434
NPIPB8	0.433
KPNB1	0.433
RPL7L1	0.432
GOLGA6L3	0.432
SNRNP70	0.432
COPB1	0.431
NPIPB5	0.431
TSPY8	0.431
SEC13	0.431
TICRR	0.43
TYMS	0.43
DISP2	0.428
COPG1	0.428
ARCN1	0.428
SCAF1	0.428
CDCA3	0.426
XYLT2	0.426
ATXN1	0.426
AAMP	0.425
RRN3	0.425
PSMC6	0.424
ZNF106	0.424
RNF4	0.424
PSMA1	0.424
RAD21	0.423
PSMB1	0.423
COX7A2L	0.423
CTAGE4	0.422
SART1	0.422
NPIPB11	0.421
OGFR	0.421
HIST2H2BF	0.42
HAP1	0.42
ATP6V0C	0.419
LRR1	0.419
NAALADL1	0.418
CBWD6	0.417
ATP6V1C1	0.416
EXOSC9	0.416
CACTIN	0.415
ZFAND5	0.415
POLR2D	0.414
UTP3	0.414
TFIP11	0.412
UQCRH	0.412
RPS7	0.412
ANKLE2	0.412
DIDO1	0.41
CDC6	0.41
POLR2J2	0.41
PSMC2	0.409
NUP160	0.409
PRIM1	0.409
ATP13A1	0.408
DTL	0.408
RFPL3	0.408
STIL	0.407
PSMD7	0.407
RRP15	0.406
PSMD11	0.406
HIST1H2BE	0.405
SFPQ	0.405
PLK1	0.405
C2orf27A	0.405
GOLGA6A	0.405
WDR43	0.404
MED17	0.404
BRD2	0.403
RBBP5	0.402
DDT	0.402
PWP2	0.402
RRP9	0.402
KLHL1	0.402
CDC73	0.402
DNTTIP2	0.402
POLE2	0.401
CDC45	0.4
AHCTF1	0.4
PPAN	0.4

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 1951
Expression level (log2 read counts): -3.7

Expression Distribution

I-set
fn3

sarcomere
Z disc