DISP2
Gene Information
- Official Symbol: DISP2
- Official Name: dispatched RND transporter family member 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 85455
- UniProt: A7MBM2
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| smoothened signaling pathway |
| cellular component |
| molecular function |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Colchicine 0.009μM R05 exp215 | 1.76 |
| UNC2400 2μM R03 exp156 | 1.77 |
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| CHD4 | 0.568 |
| COPA | 0.548 |
| ATP1A3 | 0.541 |
| RRM1 | 0.537 |
| CBWD3 | 0.528 |
| C14orf93 | 0.517 |
| NPIPB5 | 0.516 |
| CBWD5 | 0.514 |
| COPG1 | 0.512 |
| KIF3C | 0.508 |
| PAN3 | 0.498 |
| PSMB4 | 0.497 |
| CCNA2 | 0.496 |
| TCEB3C | 0.495 |
| UTP3 | 0.492 |
| DDTL | 0.492 |
| MYT1L | 0.492 |
| PCF11 | 0.49 |
| AATF | 0.488 |
| AQR | 0.488 |
| TCEB3CL2 | 0.487 |
| RPL30 | 0.485 |
| ORC1 | 0.485 |
| VASN | 0.485 |
| PAN2 | 0.482 |
| TCEB3CL | 0.481 |
| EXOSC5 | 0.481 |
| CCDC64B | 0.481 |
| SMG1 | 0.48 |
| CBWD6 | 0.478 |
| AAMP | 0.478 |
| OGFR | 0.475 |
| TFIP11 | 0.473 |
| C1QTNF9B | 0.473 |
| NAPA | 0.471 |
| RAD51 | 0.469 |
| SLC4A1 | 0.465 |
| TBC1D3H | 0.463 |
| RANBP2 | 0.462 |
| NOP16 | 0.461 |
| ANKLE2 | 0.461 |
| NARFL | 0.459 |
| MED14 | 0.458 |
| EBNA1BP2 | 0.458 |
| PPM1D | 0.458 |
| RBBP5 | 0.457 |
| RPL9 | 0.457 |
| TBC1D3F | 0.456 |
| DTL | 0.455 |
| ZFAND5 | 0.455 |
| HIST2H3C | 0.454 |
| HIST2H3A | 0.454 |
| CHCHD3 | 0.453 |
| POLR2D | 0.453 |
| SUPT5H | 0.452 |
| HIST2H2BF | 0.452 |
| SNRPA1 | 0.451 |
| TBC1D3G | 0.45 |
| ACBD4 | 0.45 |
| ATP13A1 | 0.45 |
| ZNF541 | 0.449 |
| NOL12 | 0.448 |
| RPS12 | 0.448 |
| TBC1D3C | 0.447 |
| SEC13 | 0.447 |
| HNRNPA1 | 0.446 |
| MT1E | 0.446 |
| KCTD17 | 0.446 |
| PSMD11 | 0.445 |
| HAP1 | 0.444 |
| NUMA1 | 0.444 |
| IK | 0.444 |
| PSMC6 | 0.444 |
| RPS19 | 0.443 |
| TERF1 | 0.442 |
| CDC7 | 0.441 |
| ANKLE1 | 0.44 |
| GOLGA6L3 | 0.438 |
| SNIP1 | 0.438 |
| TWISTNB | 0.436 |
| MBTD1 | 0.436 |
| PSMC2 | 0.435 |
| PSMD1 | 0.434 |
| SUPT6H | 0.432 |
| GOLGA8O | 0.431 |
| MYO1H | 0.431 |
| NSF | 0.43 |
| TSG101 | 0.429 |
| EXOSC9 | 0.429 |
| IGFN1 | 0.428 |
| CDC45 | 0.426 |
| CMYA5 | 0.426 |
| SMG7 | 0.426 |
| CDCA3 | 0.426 |
| RPS2 | 0.425 |
| VPS54 | 0.425 |
| TTC1 | 0.425 |
| POLA1 | 0.421 |
| NUP205 | 0.42 |
| POLE | 0.42 |
| GPRIN2 | 0.42 |
| RPS20 | 0.419 |
| POLR2F | 0.419 |
| DOCK6 | 0.419 |
| VPS28 | 0.418 |
| FCN2 | 0.418 |
| FAM160A1 | 0.417 |
| SF3A1 | 0.417 |
| RRP7A | 0.416 |
| HIVEP3 | 0.416 |
| AKT1S1 | 0.416 |
| GOLGA6L4 | 0.416 |
| USP35 | 0.416 |
| RPS7 | 0.415 |
| ORC6 | 0.414 |
| HK1 | 0.414 |
| WDR87 | 0.413 |
| TBC1D3 | 0.413 |
| RPSA | 0.412 |
| SCGB1C1 | 0.412 |
| TSPY8 | 0.412 |
| ATXN1 | 0.411 |
| HIST1H4B | 0.411 |
| EXOSC6 | 0.41 |
| CDH24 | 0.41 |
| CCDC116 | 0.409 |
| RNPC3 | 0.408 |
| TICRR | 0.407 |
| BYSL | 0.407 |
| RRN3 | 0.407 |
| CHST3 | 0.406 |
| GID4 | 0.406 |
| TP53TG3B | 0.403 |
| RPS3A | 0.402 |
| FBXW9 | 0.402 |
| TP53TG3 | 0.402 |
| TYMS | 0.402 |
| MED17 | 0.402 |
| TUBA8 | 0.401 |
| CEP192 | 0.401 |
| PSMA6 | 0.401 |
| TP53TG3C | 0.401 |
| SLC6A17 | 0.4 |
| RPL35 | 0.4 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 1981
- Expression level (log2 read counts): 4.4
Expression Distribution
DISP2 Expression in NALM6 Cells: 4.4
