GPRIN2 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: GPRIN2
Official Name: G protein regulated inducer of neurite outgrowth 2
Aliases and Previous Symbols: N/A
Entrez ID: 9721
UniProt: O60269
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: May be involved in neurite outgrowth. {ECO:0000269|PubMed:10480904}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Gene	Correlation
TWISTNB	0.506
TCEB3CL2	0.491
TICRR	0.487
ANKLE1	0.483
ORC1	0.476
POLR2J3	0.468
ANKLE2	0.462
TCEB3C	0.462
NPIPB5	0.457
KCTD17	0.455
PSMA6	0.454
MED17	0.451
VPS54	0.448
GID4	0.444
C14orf93	0.443
CHD4	0.442
PSMB4	0.442
TFIP11	0.44
SUPT5H	0.439
WDR75	0.439
TCEB3CL	0.438
VASN	0.437
FBXO5	0.437
PAN3	0.434
ZNF541	0.432
RPS2	0.429
C1QTNF9B	0.428
MYO1H	0.428
TBC1D3H	0.427
CACTIN	0.423
MED14	0.422
MT1E	0.42
DISP2	0.42
PLK1	0.419
RRP15	0.419
CDC6	0.415
SUPT6H	0.415
AQR	0.414
SH3BP1	0.413
NOL12	0.412
CLASP1	0.412
DTL	0.411
DNM2	0.411
AHCTF1	0.41
POLR2F	0.41
ZNF574	0.409
RUVBL2	0.409
PCF11	0.409
PSMD11	0.408
COPB2	0.407
TONSL	0.406
DDTL	0.406
CBWD3	0.405
SF3A1	0.403
SNIP1	0.403
CCDC64B	0.403
TBC1D3G	0.403
AAMP	0.401
ISCU	0.401
CGB2	0.401
NBPF10	0.4

Global Fraction of Cell Lines Where Essential: 3/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	1/28
bone	0/26
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	1/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 2155
Expression level (log2 read counts): -7.68

Expression Distribution

Last modified: 2025/12/10 20:19
by 127.0.0.1