CTAGE4
Gene Information
- Official Symbol: CTAGE4
- Official Name: CTAGE family member 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 100128553
- UniProt: Q8IX94
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Tumor-associated antigen.
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| vesicle cargo loading |
| endoplasmic reticulum exit site |
| protein secretion |
| establishment of protein localization to extracellular region |
| protein localization to extracellular region |
| peptide secretion |
| endoplasmic reticulum to Golgi vesicle-mediated transport |
| Golgi vesicle transport |
| cellular component |
| endoplasmic reticulum membrane |
| secretion by cell |
| export from cell |
| secretion |
| protein transport |
| intracellular transport |
| peptide transport |
| amide transport |
| establishment of protein localization |
| establishment of localization in cell |
| nitrogen compound transport |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| SNS-032 25μM R07 exp401 | -1.97 |
| Metformin 40μM R03 exp132 | 1.7 |
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| PRIM1 | 0.551 |
| CHD4 | 0.546 |
| PSMA6 | 0.51 |
| DDTL | 0.509 |
| GOLGA6L1 | 0.507 |
| TCEB3C | 0.502 |
| PSMB4 | 0.5 |
| CCNA2 | 0.498 |
| PDCD11 | 0.487 |
| CBWD3 | 0.483 |
| MFSD12 | 0.483 |
| ZNF830 | 0.481 |
| TP53TG3C | 0.48 |
| TP53TG3 | 0.48 |
| TP53TG3B | 0.48 |
| SLC6A17 | 0.474 |
| NOL10 | 0.474 |
| TBC1D3F | 0.474 |
| RPL35 | 0.472 |
| TBC1D3G | 0.469 |
| TCEB3CL | 0.467 |
| POLR2D | 0.466 |
| COPG1 | 0.464 |
| SYT9 | 0.464 |
| GOLGA6L3 | 0.464 |
| TSG101 | 0.458 |
| SSH2 | 0.458 |
| PSMD2 | 0.457 |
| TBC1D3H | 0.456 |
| ATP6V1B2 | 0.455 |
| VPS28 | 0.455 |
| DHX38 | 0.454 |
| ATP6V1A | 0.452 |
| SART1 | 0.451 |
| ATP6V1C1 | 0.451 |
| WDR75 | 0.451 |
| CBWD6 | 0.45 |
| LRR1 | 0.449 |
| TSPY1 | 0.447 |
| IK | 0.447 |
| CBWD5 | 0.445 |
| RPL6 | 0.444 |
| SUPT6H | 0.443 |
| RRP7A | 0.443 |
| RPS12 | 0.443 |
| C1QTNF9B | 0.443 |
| CHAF1A | 0.442 |
| PSMC1 | 0.442 |
| POLA2 | 0.442 |
| DDT | 0.44 |
| TCEB3CL2 | 0.44 |
| PSMC2 | 0.44 |
| GOLGA6L6 | 0.439 |
| DTL | 0.437 |
| GOLGA8O | 0.436 |
| RRP15 | 0.436 |
| COPE | 0.436 |
| UTP3 | 0.435 |
| RNPC3 | 0.434 |
| AATF | 0.432 |
| RAD51 | 0.432 |
| ORC6 | 0.431 |
| CHMP4B | 0.429 |
| DDX21 | 0.429 |
| NUP93 | 0.429 |
| CEP192 | 0.428 |
| PLA2G4F | 0.428 |
| EXOSC9 | 0.428 |
| POLR2A | 0.428 |
| NBPF10 | 0.428 |
| RPS2 | 0.427 |
| DDX56 | 0.427 |
| EXOSC6 | 0.424 |
| KIAA0947 | 0.424 |
| HIVEP3 | 0.423 |
| OSBP | 0.423 |
| IGFN1 | 0.422 |
| SF3A3 | 0.421 |
| TP53TG3D | 0.42 |
| UPF1 | 0.42 |
| PSMB3 | 0.418 |
| SULT2B1 | 0.418 |
| PAN3 | 0.417 |
| ORC1 | 0.417 |
| CDC5L | 0.417 |
| MT1E | 0.416 |
| TUBA8 | 0.415 |
| PSMD7 | 0.414 |
| ANKLE2 | 0.413 |
| COL2A1 | 0.413 |
| C2orf27A | 0.412 |
| PSMD3 | 0.411 |
| TICRR | 0.411 |
| PSMA7 | 0.411 |
| NSF | 0.41 |
| SF3A2 | 0.41 |
| NOL12 | 0.41 |
| PSMB2 | 0.408 |
| SEC13 | 0.408 |
| CDT1 | 0.407 |
| ACSF2 | 0.407 |
| FAM160A1 | 0.407 |
| NUMA1 | 0.406 |
| SCGB1C1 | 0.404 |
| TWISTNB | 0.404 |
| HGC6.3 | 0.403 |
| PDCD7 | 0.403 |
| DIMT1 | 0.402 |
| PSMC5 | 0.402 |
| WDR43 | 0.401 |
| RPS7 | 0.401 |
| RPS3A | 0.4 |
| NCL | 0.4 |
| ATP6V0B | 0.4 |
| AQR | 0.4 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 1866
- Expression level (log2 read counts): -1.98
Expression Distribution
CTAGE4 Expression in NALM6 Cells: -1.98