Table of Contents

Cisplatin 0.35μM R06 exp273

Mechanism of Action

Intrastrand cross-linker

Technical Notes

Protein References

  • PubChem Name: Cisplatin
  • Synonyms: CDDP; cis-Diaminodichloroplatinum
  • CAS #: 15663-27-1
  • PubChem CID: 5702198
  • IUPAC: azane;dichloroplatinum
  • INCHI Name: InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
  • INCHI Key: LXZZYRPGZAFOLE-UHFFFAOYSA-L
  • Molecular Weight: 300
  • Canonical SMILES: N.N.Cl[Pt]Cl
  • Isomeric SMILES: N/A
  • Molecular Formula: Cl2H6N2Pt

Protein Supplier

  • Supplier Name: Sigma-Aldrich
  • Catalog #: P4394
  • Lot #: N/A

Protein Characterization

  • XRPD: Expected (NH3)2PtCl2; found (NH3)2PtCl2

Dose Response Curve

  • Platform ID: Cisplatin
  • Min: 4.5895; Max: 99.6466





IC Concentration (µM)
IC10 N/A
IC20 N/A
IC30 0.2153
IC40 N/A
IC50 0.4700
IC60 N/A
IC70 N/A
IC80 N/A
IC90 N/A


Screen Summary

Screen Results

Sensitive/Resistant hits (FDR<0.05)CRANKSScore PlotTop 30 GenesScreen SimilarityTop 30 Sensitive GO termsTop 30 Resistant GO terms
2/1ScoresViewViewViewViewView