ELMSAN1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Quercetin 20μM R08 exp517	-2.43
BVD-523 15μM R02 exp67	-2.33
Mdivi-1 15μM R05 exp217	-2.21
SNS-032 25μM R07 exp401	-2.13
BML-284 0.09μM R08 exp460	-2.08
UM131593 0.1μM R01 exp58	-2.07
Bafilomycin-A1 0.009μM R08 exp454	-2.03
Dorsomorphin 5μM R07 exp357	-2.03
UM131593 0.2μM R03 exp106	-1.95
Aphidicolin 0.4μM R08 exp440	-1.92
Pimelic-diphenylamide-106 0.5μM R00 exp27	-1.79
CB-839 10μM R05 exp224	-1.78
Hydroxyurea 100μM R07 exp329	-1.76
3-Bromopyruvate 7μM R04 exp175	-1.75
Nifurtimox 1μM R03 exp141	-1.72
GSK343 3μM R03 exp124	-1.71
UMK57 1μM R01 exp59	-1.71
Actinomycin-D 0.001μM R00 exp3	-1.7

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

histone deacetylase complex
transcription factor complex
transcription regulatory region DNA binding
transcription factor binding
DNA-binding transcription factor activity
DNA-binding transcription factor activity, RNA polymerase II-specific