MAU2
Gene Information
- Official Symbol: MAU2
- Official Name: MAU2 sister chromatid cohesion factor
- Aliases and Previous Symbols: N/A
- Entrez ID: 23383
- UniProt: Q9Y6X3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with NIPBL/SCC2 which mediates the loading of the cohesin complex onto chromatin (PubMed:28167679, PubMed:22628566). Plays a role in sister chromatid cohesion and normal progression through prometaphase (PubMed:16802858, PubMed:16682347). {ECO:0000269|PubMed:16682347, ECO:0000269|PubMed:16802858, ECO:0000269|PubMed:22628566, ECO:0000269|PubMed:28167679}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 73
- Expression level (log2 read counts): 6.43