CCDC90B [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: CCDC90B
Official Name: coiled-coil domain containing 90B
Aliases and Previous Symbols: N/A
Entrez ID: 60492
UniProt: Q9GZT6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Trametinib 10μM R02 exp83	1.74
Temozolomide 200μM R04 exp189	1.77
BML-284 0.09μM R08 exp460	1.78
Wortmannin 0.5μM R00 exp37	1.81
Rifampicin 1μM R00 exp31	1.96
Azithromycin 100μM R08 exp452	2.02
BI-6727 0.0125μM R03 exp97	2.06
Mdivi-1 15μM R05 exp217	2.09
Nicotine 3000μM R08 exp510	2.16
Rapamycin 1μM R00 exp29	2.19
Cycloheximide 0.2μM R00 exp15	2.21
CCCP 0.1μM R00 exp10	2.27
Rapamycin 10μM R00 exp30	2.56

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 907
Expression level (log2 read counts): 5.68

Expression Distribution

Last modified: 2025/12/10 20:19
by 127.0.0.1