GLYR1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
UMK57 1μM R01 exp59	-2.39
HMS-I1 1μM R01 exp46	-2.08
UM131593 0.2μM R03 exp106	-1.85
Vinblastine 0.002μM R01 exp60	-1.79
BI-2536 0.0042μM R03 exp95	-1.75
Betulinic acid 10 to 15μM on day4 R05 exp222	1.71
Tubastatin-A 2.5μM R07 exp417	1.71
INK128 0.2μM R02 exp70	1.72
6-Thio-2-deoxyguanosine 2μM R06 exp259	1.82
EPZ-5676 30μM R05 exp233	1.85
Tunicamycin 0.04 to 0.125μM on day4 R07 exp420	1.88
Tunicamycin 0.04 to 0.075μM on day4 R07 exp419	1.99
Dexamethasone 0.006 to 0.015μM on day4 R07 exp352	2.13
Geldanamycin 0.015 to 0.05μM on day4 R07 exp317	2.15
Geldanamycin 0.015 to 0.025μM on day4 R07 exp316	2.26
Nicotine 3000μM R08 exp510	2.28
Rapamycin 2μM R07 exp306	2.33
Ethanol 0.01 R05 exp234	2.62
TRAIL 50ng/ml R00 exp36	2.71
TRAIL 5ng/ml R00 exp35	3.11

Global Fraction of Cell Lines Where Essential: 0/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/25
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

NADP binding
NAD binding
methylated histone binding
nucleosome
oxidoreductase activity
histone binding
nuclear speck
oxidation-reduction process
Golgi apparatus
DNA binding