TMA16 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: TMA16
Official Name: translation machinery associated 16 homolog
Aliases and Previous Symbols: N/A
Entrez ID: 55319
UniProt: Q96EY4
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
NFN1 1μM R03 exp100	-1.99
Hydroxychloroquine 30μM R08 exp490	-1.97
UM0011500 5μM R05 exp245	-1.96
YM155 0.0002μM R01 exp61	-1.91
A-395 10μM R05 exp218	-1.89
Deguelin 0.15μM R05 exp209	-1.86
VHL-ligand-1 20μM R07 exp421	-1.86
Lapatinib 5μM R01 exp47	-1.82
Benzoate 10000μM R08 exp455	-1.72
Taxol 0.002μM R01 exp54	-1.71
ONC212 0.15μM R08 exp513	1.89
Atovaquone 15μM R08 exp451	2.14

Gene	Correlation
HARS	0.537
CHCHD4	0.45
HAUS8	0.448
THG1L	0.429
ALG13	0.426
DDX20	0.425
DHPS	0.406
EFTUD1	0.405
TEN1	0.405
VEZT	0.404
SRP14	0.401

Global Fraction of Cell Lines Where Essential: 490/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	19/28
blood	8/28
bone	15/26
breast	17/33
central nervous system	45/56
cervix	3/4
colorectal	12/17
esophagus	10/13
fibroblast	1/1
gastric	12/16
kidney	17/21
liver	13/20
lung	51/75
lymphocyte	11/16
ovary	16/26
pancreas	18/24
peripheral nervous system	10/16
plasma cell	2/15
prostate	0/1
skin	16/24
soft tissue	6/9
thyroid	2/2
upper aerodigestive	17/22
urinary tract	26/29
uterus	3/5

Essentiality in NALM6

Essentiality Rank: 8350
Expression level (log2 read counts): 5.58

Expression Distribution

Last modified: 2025/12/10 20:19
by 127.0.0.1