UBE2Q2L

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Oligomycin-A 20μM R00 exp26	-3.02
SNS-032 25μM R07 exp401	-1.94
Milciclib 2μM R08 exp502	-1.78
THZ1 0.06μM R08 exp531	-1.77
Salinomycin 3.5μM R08 exp521	-1.72
Pomalidomide 20μM R07 exp391	1.7
ABT-702 5μM plus Dimethyloxaloylglycine 11μM R07 exp319	1.77
Ribavirin 10μM R01 exp52	1.78
Lapatinib 5μM R01 exp47	1.8
NN-Diethyl-meta-toluamide 100μM R05 exp237	1.87
Cerivastatin 0.15μM R05 exp226	1.89
Trichostatin-A 0.06μM R07 exp415	1.89
LB-100 2μM R05 exp210	1.9
UM131593 0.1μM R01 exp58	1.93
Wortmannin 0.5μM R00 exp37	2.01
THZ531 0.11 to 0.125μM on day4 R07 exp410	2.03
Parthenolide 2.5μM R05 exp238	2.09
NFN1 0.1μM R01 exp49	2.24
THZ531 0.11 to 0.125 to 0.35μM on day4 then day6 R07 exp412	2.33
PF-06409577 20μM R07 exp389	2.56

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution