UBL5

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 731/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	27/28
blood	28/28
bone	26/26
breast	33/33
central nervous system	56/56
cervix	4/4
colorectal	16/17
esophagus	13/13
fibroblast	1/1
gastric	16/16
kidney	19/21
liver	20/20
lung	74/75
lymphocyte	16/16
ovary	26/26
pancreas	23/24
peripheral nervous system	16/16
plasma cell	15/15
prostate	1/1
skin	24/24
soft tissue	8/9
thyroid	2/2
upper aerodigestive	22/22
urinary tract	28/29
uterus	5/5

Expression Distribution

Screen	Score
BI-2536 0.02μM R03 exp96	-1.79
Pimelic-diphenylamide-106 0.5μM R00 exp27	1.88

protein tag
positive regulation of protein targeting to mitochondrion
regulation of protein targeting to mitochondrion
positive regulation of establishment of protein localization to mitochondrion
regulation of establishment of protein localization to mitochondrion
regulation of protein targeting
positive regulation of mitochondrion organization
positive regulation of intracellular protein transport
regulation of mitochondrion organization
positive regulation of intracellular transport
regulation of intracellular protein transport
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
mRNA splicing, via spliceosome
RNA splicing, via transesterification reactions
positive regulation of cellular protein localization
regulation of intracellular transport
RNA splicing
positive regulation of protein transport
positive regulation of establishment of protein localization
mRNA processing
regulation of cellular protein localization
positive regulation of organelle organization
mRNA metabolic process
regulation of protein transport
regulation of peptide transport
regulation of establishment of protein localization
RNA processing
regulation of cellular localization
positive regulation of transport
regulation of protein localization
positive regulation of cellular component organization
regulation of organelle organization
RNA metabolic process
regulation of transport
gene expression