ANKRD40

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
MS023 2μM R03 exp134	-2.52
Betulinic acid 10 to 15μM on day4 R05 exp222	-1.95
Temozolomide 200μM R04 exp189	-1.79
Bortezomib 0.005μM R00 exp6	1.7
Disulfiram 4.3μM R06 exp281	1.71
YM155 0.0002μM R01 exp61	1.71
CCCP 1μM R00 exp11	1.74
Fluvastatin 2.2μM R06 exp282	1.74
Chloramphenicol 20μM R00 exp13	1.79
Nicotinamide 2000μM R01 exp50	1.82
Clomiphene 4.4μM R02 exp68	1.83
35°C R06 exp302	1.84
IU1-C 25μM R04 exp183	1.84
Calcipotriol 5μM R08 exp464	1.86
JQ1 0.01μM R03 exp130	1.86
Thalidomide 20μM R07 exp406	1.87
TRAIL 50ng/ml R00 exp36	1.88
Rifampicin 1μM R00 exp31	1.9
NN-Diethyl-meta-toluamide 500μM R08 exp438	1.93
IL-3 9ng/ml R08 exp493	1.94
Bisphenol F 50μM R08 exp457	1.96
Deguelin 0.15μM R05 exp209	1.99
CCCP 0.1μM R00 exp10	2
Rucaparib 6.5μM R08 exp520	2.02
Dihydrosphingosine 8μM R08 exp476	2.13
UM131593 0.1μM R01 exp58	2.15
HMS-I2 10μM R06 exp288	2.18
Rifampicin 10μM R00 exp32	2.45
Chloramphenicol 2μM R00 exp12	2.51
IWR1 50μM R08 exp495	2.52
Nicotinamide 1000μM R03 exp101	2.57

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Ank 2
Ank

cellular component
molecular function