CEP44 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: CEP44
Official Name: centrosomal protein 44
Aliases and Previous Symbols: N/A
Entrez ID: 80817
UniProt: Q9C0F1
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Parthenolide 2.5μM R05 exp238	-1.98
Colchicine 0.009μM R05 exp215	-1.9
NFN1 0.1μM R01 exp49	-1.9
HMS-I1 1μM R01 exp46	-1.83
Demecolcine 0.03μM R05 exp228	-1.72
Vinblastine 0.002μM R01 exp60	-1.71
RO-3307 4.7μM R02 exp80	1.78
TNF-alpha 44ng/ml R08 exp533	1.79
LY2090314 0.003μM R08 exp500 no dilution day6	1.8
Rotenone 0.07μM R08 exp431	1.99
Methotrexate 0.01μM R08 exp501	2.03
MLN-4924 2μM R00 exp22	2.31
PU-H71 1μM R08 exp515	2.37
Hinokiflavone 12μM R08 exp487	2.62
Cytochalasin-B 5μM R07 exp349	3.93
Tozasertib 0.1μM R07 exp414	4.15
Latrunculin-B 10μM R07 exp374	5.54

Gene	Correlation
C14orf80	0.622
TUBD1	0.579
CEP120	0.547
CASP2	0.521
C16orf59	0.516
CCDC41	0.515
PIDD	0.494
C2CD3	0.494
TUBE1	0.49
KIAA0753	0.469
CRADD	0.464
FGFR1OP	0.445
ODF2	0.445
KIAA1731	0.437
CEP76	0.435
PIBF1	0.434
ANKRD26	0.423
CEP128	0.422
TKT	0.42
SRP9	0.401

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 14918
Expression level (log2 read counts): 5.14

Expression Distribution

Last modified: 2026/01/07 22:36
by 127.0.0.1