ELP5

Gene Information
  • Official Symbol: ELP5
  • Official Name: elongator acetyltransferase complex subunit 5
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 23587
  • UniProt: Q8TE02
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration (By similarity). May be involved in TP53-mediated transcriptional regulation. {ECO:0000250, ECO:0000269|PubMed:16850183}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1222
  • Expression level (log2 read counts): 5.96

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1