FAM86B2 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: FAM86B2
Official Name: family with sequence similarity 86 member B2
Aliases and Previous Symbols: N/A
Entrez ID: 653333
UniProt: P0C5J1
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Gene	Correlation
HGC6.3	0.522
VASN	0.485
OGFR	0.461
RPS2	0.459
TWISTNB	0.457
POLA1	0.453
ZFAND5	0.448
RRM1	0.44
NCAPG	0.438
TBC1D3H	0.437
CDC73	0.437
OR10G3	0.437
C14orf93	0.437
PSMB4	0.436
TBC1D3C	0.435
RPS20	0.428
PSMA6	0.427
PWP2	0.425
CHD4	0.424
RPL35	0.424
MMS22L	0.422
HAP1	0.421
TBC1D3I	0.421
TBC1D3K	0.421
TBC1D3L	0.421
TBC1D3E	0.421
ELMOD3	0.421
TCEB3CL2	0.42
NUP160	0.419
SSH2	0.418
CCNA2	0.416
STIL	0.416
PALB2	0.415
FAM160A1	0.414
PSMD2	0.413
RPSA	0.41
ZNF106	0.409
TCEB3C	0.409
EXOSC9	0.409
S1PR4	0.409
POLR2J3	0.408
PSMA7	0.407
RAD51	0.407
NOP16	0.407
C1QTNF9B	0.405
PSAP	0.405
RNF121	0.405
SLC38A7	0.404
KPNB1	0.402
GGA3	0.402
ATXN1	0.4

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 2230
Expression level (log2 read counts): -0.87

Expression Distribution

Last modified: 2026/01/07 22:36
by 127.0.0.1