HMHA1

Gene Information
  • Official Symbol: ARHGAP45
  • Official Name: Rho GTPase activating protein 45
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 23526
  • UniProt: Q92619
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading. However, also contains N-terminally a BAR-domin which is able to play an autoinhibitory effect on this RhoGAP activity. {ECO:0000269|PubMed:24086303}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1152
  • Expression level (log2 read counts): 7.29

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1