NSUN2

• Official Symbol: NSUN2
• Official Name: NOP2/Sun RNA methyltransferase 2
• Aliases and Previous Symbols: N/A
• Entrez ID: 54888
• UniProt: Q08J23
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011].
• UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 3379
• Expression level (log2 read counts): 7.82

Expression Distribution

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NSUN2 Expression in NALM6 Cells: 7.82