SULT1A4

Entrez Summary: N/A
UniProt Summary: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

aryl sulfotransferase activity
3-phosphoadenosine 5-phosphosulfate metabolic process
purine ribonucleoside bisphosphate metabolic process
catecholamine metabolic process
catechol-containing compound metabolic process
phenol-containing compound metabolic process
ribonucleoside bisphosphate metabolic process
nucleoside bisphosphate metabolic process
purine nucleoside bisphosphate metabolic process
steroid metabolic process
purine ribonucleotide metabolic process
ribonucleotide metabolic process
purine nucleotide metabolic process
ribose phosphate metabolic process
sulfur compound metabolic process
purine-containing compound metabolic process
nucleotide metabolic process
nucleoside phosphate metabolic process
organic hydroxy compound metabolic process
nucleobase-containing small molecule metabolic process
organophosphate metabolic process
oxoacid metabolic process
organic acid metabolic process
carbohydrate derivative metabolic process
lipid metabolic process
small molecule metabolic process