Pfam Domains GO Terms
| Misat Myo SegII |
| Tubulin |
| mitochondrion distribution |
| mitochondrial genome maintenance |
| mitotic spindle assembly |
| mitochondrion localization |
| mitotic spindle organization |
| spindle assembly |
| microtubule cytoskeleton organization involved in mitosis |
| mitotic sister chromatid segregation |
| sister chromatid segregation |
| mitotic nuclear division |
| spindle organization |
| mitochondrial outer membrane |
| nuclear chromosome segregation |
| chromosome segregation |
| nuclear division |
| organelle fission |
| mitochondrion organization |
| microtubule cytoskeleton organization |
| organelle localization |
| mitotic cell cycle process |
| microtubule-based process |
| mitotic cell cycle |
| organelle assembly |
| molecular function |
| cell cycle process |
| chromosome organization |
| cytoskeleton organization |
| cell cycle |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Gene | Correlation |
|---|---|
| RPP21 | 0.535 |
| GEMIN8 | 0.529 |
| TEN1 | 0.522 |
| DHRSX | 0.504 |
| GEMIN7 | 0.494 |
| THG1L | 0.473 |
| TRMT61A | 0.466 |
| GTF3C6 | 0.465 |
| C15orf41 | 0.465 |
| GEMIN6 | 0.464 |
| VEZT | 0.46 |
| PPCS | 0.459 |
| URM1 | 0.459 |
| ELP6 | 0.454 |
| PPP6C | 0.445 |
| TAMM41 | 0.444 |
| PPCDC | 0.44 |
| SARS2 | 0.44 |
| ADSL | 0.439 |
| MOCS3 | 0.439 |
| EFTUD1 | 0.438 |
| PGM3 | 0.437 |
| ELP3 | 0.437 |
| ALG1 | 0.434 |
| CTU1 | 0.434 |
| PMVK | 0.432 |
| ALG13 | 0.431 |
| DR1 | 0.43 |
| SSB | 0.424 |
| UAP1 | 0.423 |
| PTAR1 | 0.422 |
| PDCD5 | 0.42 |
| ZRSR2 | 0.418 |
| DPH1 | 0.417 |
| RFT1 | 0.414 |
| BCS1L | 0.41 |
| RPIA | 0.41 |
| FANCC | 0.409 |
| MBTPS2 | 0.408 |
| TXNL4B | 0.407 |
| ELP2 | 0.405 |
| TBCB | 0.404 |
| ATXN10 | 0.402 |
| NHP2 | 0.4 |
| DOLK | 0.4 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 1/1 |
| bile duct | 12/28 |
| blood | 16/28 |
| bone | 4/26 |
| breast | 11/33 |
| central nervous system | 30/56 |
| cervix | 1/4 |
| colorectal | 5/17 |
| esophagus | 3/13 |
| fibroblast | 1/1 |
| gastric | 6/16 |
| kidney | 5/21 |
| liver | 10/20 |
| lung | 27/75 |
| lymphocyte | 4/16 |
| ovary | 13/26 |
| pancreas | 9/24 |
| peripheral nervous system | 4/16 |
| plasma cell | 5/15 |
| prostate | 1/1 |
| skin | 8/24 |
| soft tissue | 6/9 |
| thyroid | 2/2 |
| upper aerodigestive | 9/22 |
| urinary tract | 16/29 |
| uterus | 2/5 |
Expression Distribution