RPIA

Gene Information
  • Official Symbol: RPIA
  • Official Name: ribose 5-phosphate isomerase A
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 22934
  • UniProt: P49247
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18. [provided by RefSeq, Mar 2010].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 4224
  • Expression level (log2 read counts): 5.59

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1