SGC2043 10μM R03 exp152 [The Human Chemical-Genetic Interaction Map Project]

Inactive control for A-196 (SUV420H1/H2 inhibitor)

Class / Subclass 1: Gene Regulation / Epigenetic Inhibitor

Compound References

PubChem Name: N/A
Synonyms: N/A
CAS #: N/A
PubChem CID: N/A
IUPAC: N/A
INCHI Name: N/A
INCHI Key: N/A
Molecular Weight: 373.29
Canonical SMILES: N/A
Isomeric SMILES: N/A
Molecular Formula: C19H18Cl2N4

Compound Supplier

Supplier Name: Structural Genomics Consortium
Catalog #: N/A
Lot #: N/A

Compound Characterization

HRMS (ESI-TOF) m/z: (M+H)+ Calcd for C19H18Cl2N4 373.09813; found 373.10112

Dose Response Curve

Platform ID: SGC2043
Min: -1.6023; Max: 41.8559

IC	Concentration (µM)
IC10	N/A
IC20	12.7645
IC30	16.9874
IC40	N/A
IC50	N/A
IC60	N/A
IC70	N/A
IC80	N/A
IC90	N/A

Screen Summary

Round: 03
Dose: 10µM
Days of incubation: 8
Doublings: 7.3
Numbers of reads: 12851647

Sensitive/Resistant hits (FDR<0.05)	CRANKS	Score Plot	Top 30 Genes	Screen Similarity	Top 30 Sensitive GO terms	Top 30 Resistant GO terms
1/0	Scores	View	View	View	View	View

Gene	CRANKS Score	FDR
FLVCR1	-4.60	<0.01
SLC7A5	-2.69	0.06
PDSS1	-2.67	0.18
PGM3	-2.36	0.24
RFC2	-2.36	0.33
COG6	-2.33	0.18
SLC5A3	-2.33	0.18
SEC62	-2.31	0.18
LLGL1	-2.29	0.18
DCAF15	-2.27	0.40
GCLC	-2.23	0.32
COQ9	-2.20	0.25
KIAA1432	-2.16	0.28
COG7	-2.11	0.32
CEPT1	-2.07	0.33
PLEKHB1	-2.02	0.39
IL12B	-2.02	0.39
KCNS1	-1.98	0.43
WBSCR16	-1.98	0.63
FNTB	-1.95	0.57
PPARGC1B	-1.94	0.60
EEFSEC	-1.93	0.57
PCK2	-1.92	0.53
TMEM242	-1.91	0.53
ZMYND12	-1.91	0.53
ALG1	-1.91	0.57
SRF	-1.91	0.57
LZTR1	-1.90	0.54
ATP6V1G1	-1.89	0.57
NDUFA10	-1.88	0.57
MFAP1	1.88	0.61
GPT	1.89	0.55
NIPBL	1.89	0.61
OR52E6	1.89	0.55
VHLL	1.90	0.55
RBPMS	1.91	0.55
RPP40	1.92	0.55
DNAAF1	1.92	0.55
RPL11	1.92	0.63
HMGB2	1.93	0.55
CDC23	1.94	0.55
CDC42BPA	1.95	0.55
LCN1	1.97	0.55
KIF23	1.98	0.62
SLC5A1	1.99	0.55
CD52	2.02	0.55
TAS2R13	2.02	0.55
COPE	2.05	0.72
DROSHA	2.08	0.56
TMEM2	2.11	0.55
CTTNBP2	2.12	0.55
POLR3B	2.14	0.55
FERMT2	2.15	0.55
FAM47E	2.17	0.55
DARS	2.17	0.55
SHFM1	2.21	0.60
TPX2	2.32	0.55
FAM104B	2.35	0.48
OR10G3	2.41	0.52
CAPZA2	2.54	0.31

Last modified: 2026/01/15 21:36
by 127.0.0.1