FAM58A
Gene Information
- Official Symbol: CCNQ
- Official Name: cyclin Q
- Aliases and Previous Symbols: N/A
- Entrez ID: 92002
- UniProt: Q8N1B3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
- UniProt Summary: Activating cyclin for the cyclin-associated kinase CDK10. {ECO:0000269|PubMed:18297069, ECO:0000269|PubMed:24218572}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 5279
- Expression level (log2 read counts): 4.02