C1orf27 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: ODR4
Official Name: odr-4 GPCR localization factor homolog
Aliases and Previous Symbols: N/A
Entrez ID: 54953
UniProt: Q5SWX8
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: May play a role in the trafficking of a subset of G- protein coupled receptors. {ECO:0000250|UniProtKB:Q8I7F8}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Golgicide-A 4μM R03 exp122	-2.97
Bortezomib 0.005μM R00 exp6	-2.8
Thapsigargin 0.005μM R07 exp407	-2.3
Methotrexate 0.01μM R08 exp501	-2.15
proTAME 5μM R04 exp187	-2.15
Calcium Ionophore 0.4μM R07 exp342	-1.92
Ethanol 0.01 R05 exp234	-1.92
Radicicol 0.16μM R05 exp242	-1.86
Aminopterin 0.005μM R07 exp335	-1.84
Senexin-A 25μM R07 exp400	1.73
QNZ 0.01μM R08 exp439	1.74
Nicotine 3000μM R08 exp510	1.77
AICAR 240μM R03 exp116	1.86
Citral 50μM R06 exp274	1.9
Taxol 0.004μM R03 exp103	1.94
BI-6727 0.0125μM R03 exp97	2.1
Phenformin 20μM R03 exp143	2.29
BI-2536 0.0042μM R03 exp95	2.75

Gene	Correlation
UFSP2	0.771
UFC1	0.767
UBA5	0.748
UFM1	0.745
UFL1	0.667
DDRGK1	0.596
ALG6	0.529
UBE2J1	0.526
TMED10	0.509
DNAJB11	0.506
SBDS	0.496
DNAJC3	0.487
ATP5O	0.461
ALG8	0.46
UBE2G2	0.455
SEC62	0.452
MANF	0.449
ASB7	0.437
ATP5B	0.436
GTF3C4	0.431
ALG5	0.428
ATP5A1	0.422
EIF1AX	0.417
DERL1	0.415
DERL2	0.41
EFTUD1	0.407
ALG1	0.4

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	1/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 5974
Expression level (log2 read counts): 5.2

Expression Distribution

Last modified: 2026/01/07 22:36
by 127.0.0.1