ZNF330

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
NN-Diethyl-meta-toluamide 100μM R05 exp237	-2
Dexamethasone 0.006 to 0.015μM on day4 R07 exp352	-1.93
Epothilone-B 0.0015μM R05 exp231	-1.93
GSK461364A 0.005μM R03 exp125	-1.86
UM0011500 5μM R05 exp245	-1.73
UMK57 0.6μM R03 exp107	-1.72
UM0125461 0.74μM R02 exp84	1.84
Dynasore 7μM R08 exp436	1.97
ABT-702 5μM plus CoCl2 18μM R07 exp320	2.09
Pterostilbene 16μM R02 exp78	2.09
4-Nitroquinoline-1-oxide 0.5μM R08 exp446	2.39
Resveratrol 16μM R03 exp147	2.54
Rucaparib 6.5μM R08 exp520	2.71
Aphidicolin 0.4μM R08 exp440	2.83
Olaparib 4μM R08 exp512	3.02

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Gene	Correlation
SLFN11	0.469
RWDD4	0.422

chromosome, centromeric region
midbody
zinc ion binding
nucleolus