ACTR10
Gene Information
- Official Symbol: ACTR10
- Official Name: actin related protein 10
- Aliases and Previous Symbols: N/A
- Entrez ID: 55860
- UniProt: Q9NZ32
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Actin |
GO Terms
| retrograde axonal transport of mitochondrion |
| dynactin complex |
| axonal transport of mitochondrion |
| retrograde axonal transport |
| mitochondrion transport along microtubule |
| establishment of mitochondrion localization, microtubule-mediated |
| establishment of mitochondrion localization |
| mitochondrion localization |
| axonal transport |
| axon cytoplasm |
| axo-dendritic transport |
| organelle transport along microtubule |
| azurophil granule lumen |
| antigen processing and presentation of exogenous peptide antigen via MHC class II |
| antigen processing and presentation of peptide antigen via MHC class II |
| antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
| ficolin-1-rich granule lumen |
| transport along microtubule |
| cytoskeleton-dependent intracellular transport |
| antigen processing and presentation of exogenous peptide antigen |
| microtubule-based transport |
| antigen processing and presentation of exogenous antigen |
| antigen processing and presentation of peptide antigen |
| endoplasmic reticulum to Golgi vesicle-mediated transport |
| antigen processing and presentation |
| microtubule-based movement |
| establishment of organelle localization |
| Golgi vesicle transport |
| neutrophil degranulation |
| neutrophil activation involved in immune response |
| neutrophil mediated immunity |
| neutrophil activation |
| granulocyte activation |
| leukocyte degranulation |
| myeloid leukocyte mediated immunity |
| myeloid cell activation involved in immune response |
| organelle localization |
| myeloid leukocyte activation |
| leukocyte activation involved in immune response |
| cell activation involved in immune response |
| microtubule-based process |
| regulated exocytosis |
| leukocyte mediated immunity |
| exocytosis |
| leukocyte activation |
| secretion by cell |
| export from cell |
| cell activation |
| immune effector process |
| secretion |
| intracellular transport |
| movement of cell or subcellular component |
| establishment of localization in cell |
| immune response |
| extracellular region |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| Lead acetate 2000μM R08 exp498 no dilution day6 | -2.49 |
| Ethambutol 25μM R08 exp481 | -1.92 |
| EPZ-5676 30μM R05 exp233 | -1.91 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 225/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 1/1 |
| 909776.0 | 0/1 |
| bile duct | 8/28 |
| blood | 10/28 |
| bone | 13/26 |
| breast | 8/33 |
| central nervous system | 24/56 |
| cervix | 2/4 |
| colorectal | 2/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 4/16 |
| kidney | 12/21 |
| liver | 7/20 |
| lung | 16/75 |
| lymphocyte | 4/16 |
| ovary | 6/26 |
| pancreas | 4/24 |
| peripheral nervous system | 9/16 |
| plasma cell | 2/15 |
| prostate | 1/1 |
| skin | 6/24 |
| soft tissue | 2/9 |
| thyroid | 1/2 |
| upper aerodigestive | 8/22 |
| urinary tract | 11/29 |
| uterus | 1/5 |
Essentiality in NALM6
- Essentiality Rank: 985
- Expression level (log2 read counts): 5.11
Expression Distribution
ACTR10 Expression in NALM6 Cells: 5.11
