GAGE2A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
CFI-400945 25μM R08 exp469	-2.79
GSK461364A 0.1μM R03 exp126	-2.58
Cyclosporin-A 0.8μM R07 exp347	-2.25
Actinomycin-D 0.01μM R00 exp4	-2.23
Prochlorperazine 5.2μM R02 exp77	-2.14
Rapamycin 0.001μM R08 exp429	-2.12
LLY-283 2.6μM R06 exp290	-2.08
VHL-ligand-1 20μM R07 exp421	-2.06
Atovaquone 15μM R08 exp451	-1.99
Rapamycin 2μM plus Cyclosporin-A 3μM R07 exp307	-1.98
BI-6727 0.04μM R03 exp98	-1.96
MK-1775 0.32μM R02 exp75	-1.92
NN-Dimethylsphingosine 2.5μM R08 exp508	-1.88
Nocodazole 0.2μM R00 exp24	-1.86
A-769662 20μM R07 exp331	-1.83
ONC212 0.15μM R08 exp513	-1.83
Dihydrosphingosine 8μM R08 exp476	-1.81
Monensin 0.3μM R08 exp507	-1.79
Hydroxyurea 100μM R07 exp329	-1.76
Fas-L 44ng/ml R08 exp482	-1.75
Aphidicolin 0.04μM R06 exp263	1.79
BS-181 20μM R08 exp461	1.83
Geldanamycin 0.01μM R05 exp235	1.96
Cholesterol 0.003 to 0.006 to 0.1μM on day2 then day6 R08 exp471	2.07
Bisphenol F 50μM R08 exp457	2.1
NN-Diethyl-meta-toluamide 100μM R05 exp237	2.3
Bisphenol S 100μM R08 exp458	2.36
Golgicide-A 4μM R03 exp122	2.44

Global Fraction of Cell Lines Where Essential: 18/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	2/28
blood	0/26
bone	0/26
breast	1/30
central nervous system	0/49
cervix	0/4
colorectal	1/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	1/18
liver	0/19
lung	1/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	1/15
plasma cell	0/12
prostate	0/1
skin	3/20
soft tissue	0/9
thyroid	1/2
upper aerodigestive	3/22
urinary tract	0/28
uterus	0/5

Expression Distribution