USO1

Entrez Summary: N/A
UniProt Summary: General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. {ECO:0000250|UniProtKB:P41542}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Fluvastatin 2.2μM R06 exp282	-3.52
Myriocin 25μM R06 exp293	-3.29
Cerivastatin 0.15μM R05 exp226	-3.19
Brefeldin A 0.02μM R00 exp8	-3.03
Ethanol 0.01 R05 exp234	-2.44
Pterostilbene 16μM R02 exp78	-1.99
GSK591 2.6μM R03 exp128	-1.97
Tunicamycin 0.04 to 0.075μM on day4 R07 exp419	-1.97
All-trans-Retinoic-Acid 40μM R07 exp334	-1.96
Ethanol 0.003 R08 exp437	-1.91
Tunicamycin 0.04μM R07 exp418	-1.86
Cannabidiol 20μM R08 exp466	-1.78
Citral 75μM R06 exp275	-1.78
BS-181 20μM R08 exp461	-1.77
Salubrinal 20μM R07 exp399	-1.73
Parthenolide 2.5μM R05 exp238	-1.72
Aphidicolin 0.04μM R06 exp263	-1.71
B02 10μM R08 exp453	-1.71
Etoposide 0.3μM R05 exp199	1.72
HMS-I1 10μM R06 exp256	1.77
Mubritinib 0.2μM R02 exp65	1.79
Mitomycin-C 0.06μM R08 exp503	1.8
Etoposide 1μM R00 exp19	1.84
CR131-b 0.005μM R08 exp474	1.96
TRAIL 50ng/ml R00 exp36	1.96
CI-1040 9.5μM R08 exp472	2.11
6-Thio-2-deoxyguanosine 2μM R06 exp259	2.16
TRAIL 5ng/ml R00 exp35	2.5
CoCl2 18μM R07 exp346	2.79
Doxorubicin 0.02μM R08 exp478	3.15
Milciclib 2μM R08 exp502	3.19

Expression Distribution