SLC39A10
Gene Information
- Official Symbol: SLC39A10
- Official Name: solute carrier family 39 member 10
- Aliases and Previous Symbols: N/A
- Entrez ID: 57181
- UniProt: Q9ULF5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: May act as a zinc-influx transporter. {ECO:0000269|PubMed:17359283}.
Pfam Domains GO Terms
Pfam Domains
| Zip |
GO Terms
| positive regulation of protein tyrosine phosphatase activity |
| regulation of protein tyrosine phosphatase activity |
| zinc ion import across plasma membrane |
| positive regulation of B cell receptor signaling pathway |
| negative regulation of B cell apoptotic process |
| regulation of B cell apoptotic process |
| zinc ion transmembrane transporter activity |
| positive regulation of phosphoprotein phosphatase activity |
| zinc ion transmembrane transport |
| positive regulation of antigen receptor-mediated signaling pathway |
| regulation of B cell receptor signaling pathway |
| zinc ion transport |
| negative regulation of lymphocyte apoptotic process |
| cellular zinc ion homeostasis |
| positive regulation of phosphatase activity |
| zinc ion homeostasis |
| positive regulation of B cell proliferation |
| positive regulation of protein dephosphorylation |
| negative regulation of leukocyte apoptotic process |
| regulation of lymphocyte apoptotic process |
| positive regulation of dephosphorylation |
| regulation of B cell proliferation |
| regulation of antigen receptor-mediated signaling pathway |
| inorganic cation import across plasma membrane |
| inorganic ion import across plasma membrane |
| regulation of leukocyte apoptotic process |
| import across plasma membrane |
| cellular transition metal ion homeostasis |
| regulation of phosphoprotein phosphatase activity |
| transition metal ion transport |
| positive regulation of lymphocyte proliferation |
| transition metal ion homeostasis |
| positive regulation of mononuclear cell proliferation |
| positive regulation of leukocyte proliferation |
| regulation of protein dephosphorylation |
| positive regulation of B cell activation |
| regulation of phosphatase activity |
| regulation of B cell activation |
| regulation of lymphocyte proliferation |
| regulation of mononuclear cell proliferation |
| regulation of dephosphorylation |
| regulation of leukocyte proliferation |
| divalent metal ion transport |
| divalent inorganic cation transport |
| positive regulation of lymphocyte activation |
| positive regulation of leukocyte activation |
| positive regulation of cell activation |
| cellular divalent inorganic cation homeostasis |
| divalent inorganic cation homeostasis |
| regulation of lymphocyte activation |
| cellular metal ion homeostasis |
| inorganic cation transmembrane transport |
| regulation of leukocyte activation |
| cation transmembrane transport |
| metal ion homeostasis |
| cellular cation homeostasis |
| metal ion transport |
| regulation of cell activation |
| cellular ion homeostasis |
| inorganic ion transmembrane transport |
| import into cell |
| cation homeostasis |
| inorganic ion homeostasis |
| cellular chemical homeostasis |
| positive regulation of hydrolase activity |
| ion homeostasis |
| cation transport |
| positive regulation of immune response |
| negative regulation of apoptotic process |
| cellular homeostasis |
| negative regulation of programmed cell death |
| positive regulation of cell population proliferation |
| ion transmembrane transport |
| negative regulation of cell death |
| chemical homeostasis |
| positive regulation of phosphate metabolic process |
| positive regulation of phosphorus metabolic process |
| regulation of immune response |
| positive regulation of immune system process |
| positive regulation of protein modification process |
| regulation of hydrolase activity |
| transmembrane transport |
| ion transport |
| integral component of plasma membrane |
| positive regulation of catalytic activity |
| regulation of apoptotic process |
| regulation of programmed cell death |
| positive regulation of cellular protein metabolic process |
| regulation of cell population proliferation |
| homeostatic process |
| positive regulation of signal transduction |
| regulation of immune system process |
| regulation of cell death |
| positive regulation of protein metabolic process |
| positive regulation of molecular function |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of protein modification process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 27/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 4/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 5/33 |
| central nervous system | 1/56 |
| cervix | 1/4 |
| colorectal | 0/17 |
| esophagus | 1/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 1/21 |
| liver | 1/20 |
| lung | 3/75 |
| lymphocyte | 0/16 |
| ovary | 1/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 1/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 11520
- Expression level (log2 read counts): 5.54
Expression Distribution
SLC39A10 Expression in NALM6 Cells: 5.54
