Fas-L 44ng/ml R08 exp482 [The Human Chemical-Genetic Interaction Map Project]

Ligand for Fas receptor, triggers apoptosis

Class / Subclass 1: Signal Transduction / Other Receptor Agonist

Compound References

PubChem Name: N/A
Synonyms: N/A
CAS #: N/A
PubChem CID: N/A
IUPAC: N/A
INCHI Name: N/A
INCHI Key: N/A
Molecular Weight: 17.9kDa
Canonical SMILES: N/A
Isomeric SMILES: N/A
Molecular Formula: HHHHHHHHPS PPPEKKELRK VAHLTGKSNS RSMPLEWEDT YGIVLLSGVK YKKGGLVINE

Compound Supplier

Supplier Name: PeproTech
Catalog #: 310-03H
Lot #: 0217496 B1717

Compound Characterization

Characterization data not available.

Dose Response Curve

Platform ID: Fas_L
Min: -13.1002; Max: 11.4956

IC	Concentration (µM)
IC10	N/A
IC20	N/A
IC30	N/A
IC40	N/A
IC50	N/A
IC60	N/A
IC70	N/A
IC80	N/A
IC90	N/A

Screen Summary

Round: 08
Dose: 44ng/mL
Days of incubation: 8
Doublings: 6.9
Numbers of reads: 16827520

Sensitive/Resistant hits (FDR<0.05)	CRANKS	Score Plot	Top 30 Genes	Screen Similarity	Top 30 Sensitive GO terms	Top 30 Resistant GO terms
1/0	Scores	View	View	View	View	View

Gene	CRANKS Score	FDR
QSER1	-2.85	0.05
GARS	-2.83	0.76
DARS2	-2.75	0.55
ISLR	-2.29	0.52
ADSL	-2.25	0.76
SPCS1	-2.20	0.55
ADAMTS3	-2.18	0.52
GPR173	-2.16	0.52
TTC4	-2.16	0.52
OR8G5	-2.14	0.52
RSRC2	-2.11	0.81
SNAPC5	-2.09	0.76
NR2F1	-2.06	0.55
TRIAP1	-2.06	0.76
RBM42	-1.94	0.76
DCUN1D2	-1.93	0.76
LOC643802	-1.90	0.77
CADPS	-1.89	0.76
KIAA1958	-1.89	0.76
HNRNPH3	-1.88	0.76
LRRC14B	-1.87	0.76
TEX10	-1.87	0.76
ATIC	-1.86	0.76
OR10K2	-1.86	0.76
CRISPLD1	-1.84	0.76
FAM207A	-1.83	0.76
TSPAN32	-1.83	0.76
SMC1A	-1.82	0.81
PDE6G	-1.82	0.76
PARK7	-1.81	0.76
TSGA13	1.92	0.60
KRTAP10-3	1.92	0.60
ABCA6	1.93	0.60
CD79A	1.95	0.60
PSMD14	1.96	0.84
DNAJC7	1.97	0.54
LAYN	1.97	0.54
PCNXL3	1.99	0.60
SHFM1	2.00	0.80
ETF1	2.03	0.60
MKL2	2.03	0.54
PSEN2	2.09	0.54
ZNF254	2.09	0.50
MIR205HG	2.11	0.85
PSMD3	2.12	0.84
GTPBP4	2.13	0.63
IL1RL2	2.14	0.54
TAF10	2.19	0.50
KANSL2	2.20	0.50
PRR14	2.21	0.50
DNAJA1	2.22	0.50
CLLU1	2.23	0.54
NXNL1	2.26	0.50
POLD2	2.28	0.60
ZIM2	2.31	0.50
NUDT18	2.34	0.60
TRAPPC8	2.48	0.54
NUP133	2.55	0.30
CSNK1A1	2.74	0.32
XAB2	3.18	0.60

Last modified: 2026/01/15 21:36
by 127.0.0.1