COG5

Gene Information
  • Official Symbol: COG5
  • Official Name: component of oligomeric golgi complex 5
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 10466
  • UniProt: Q9UP83
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.[provided by RefSeq, Jan 2011].
  • UniProt Summary: Required for normal Golgi function. {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 10813
  • Expression level (log2 read counts): 5.46

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1