RGP1

Gene Information
  • Official Symbol: RGP1
  • Official Name: RGP1 homolog, RAB6A GEF complex partner 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 9827
  • UniProt: Q92546
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1- RGP1 complex participates in the recycling of mannose-6-phosphate receptors. {ECO:0000269|PubMed:23091056}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 2800
  • Expression level (log2 read counts): 5.52

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1