MYH7B

Gene Information
  • Official Symbol: MYH7B
  • Official Name: myosin heavy chain 7B
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 57644
  • UniProt: A7E2Y1
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010].
  • UniProt Summary: Involved in muscle contraction. {ECO:0000269|PubMed:11919279}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1946
  • Expression level (log2 read counts): 3.05

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1