SLC22A14

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
UM0131023 0.05μM R05 exp248	-2.55
ABT-702 5μM plus Dimethyloxaloylglycine 11μM R07 exp319	-2.44
UMK57 1μM R01 exp59	-2.26
Actinomycin-D 0.001μM R00 exp3	-2.21
MSC2530818 10μM R07 exp379	-2.21
Tunicamycin 0.04μM R07 exp418	-2.14
2-Methoxyestradiol 0.2μM R01 exp40	-2.08
Bortezomib 0.005μM R00 exp6	-2
Senexin-A 25μM R07 exp400	-2
R-DABN 8μM R03 exp111	-1.96
BI-D1870 2μM R04 exp162	-1.93
Vincristine 0.0005μM R04 exp190	-1.91
Monensin 0.3μM R08 exp507	-1.83
HMS-I1 10μM R06 exp256	-1.78
GW501516 25μM R06 exp285	-1.76
Cadmium 60μM R08 exp462	-1.74
NN-Dimethylsphingosine 2.5μM R08 exp508	-1.74
Bafilomycin-A1 0.009μM R08 exp454	-1.71
Pimelic-diphenylamide-106 0.5μM R00 exp27	-1.71
Ethambutol 25μM R08 exp481	1.78
SGC0946 7μM R03 exp151	1.82

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

MFS 1
Sugar tr

organic cation transmembrane transporter activity
organic cation transport
cation transport
transmembrane transport
ion transport
integral component of plasma membrane